I have the same problem but on my development machine. I just took over a project that uses several Intersoft controls. I get the error:

SCRIPT5007: The value of the property 'InitWebPaneManager' is null or undefined, not a Function object
Default.aspx, line 423 character 1

SCRIPT5007: The value of the property 'OnWebPMRSC' is null or undefined, not a Function object
Default.aspx, line 422 character 1

SCRIPT5009: 'IS' is undefined
Default.aspx, line 439 character 1

SCRIPT5007: The value of the property 'OnWebPMRSC' is null or undefined, not a Function object
Default.aspx, line 422 character 1

As well as several others when trying to run my app.

It actually looks like some script is not getting written when the page is rendered on the client. I have tried it using Crome, I.E. 9 and FireFox all with the same error.

As I said, I just took over the project so I had to unregister the licenses on the former developers machine and then reregistered them on my own after tech support said they had me setup.

Any help in this scenario?